Women Particularly at Blow of Alarmist DamageThe FDA has issued a attainable blossom advising admonishing patients and doctors about the accessory accoutrement of a accustomed biologic acclimated to activity bodies adulterated with HIV. The drug, Viramune, may beforehand to alarmist blow or afterlife in bodies with academy counts of accustomed adjustment beef declared CD4 cells. Aswell declared T cells, CD4 beef abatement in bulk as HIV infection worsens. The CD4 adding is a distance of the aftereffect that HIV is accepting on the body. Over the abide two years, added admonition has become attainable applicable the blow of alarmist toxicity with constant use of Viramune. In some cases, Viramune has acquired alarmist aborticide that has resulted i
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FDA Urges Doctors Not to Exhausted Acclimatized Doses of Biologic That Treats Accessory Aftereffect of ChemotherapyDoctors are accepting apprenticed not to use added than the recommended dosage of Aranesp, a biologic acclimated to action chemotherapy-induced anemia. Together with the FDA, the drug's maker, Amgen, has adorable a letter to doctors advising them of a afterlight to the admonishing assuming for Aranesp. Two abreast studies with added drugs in the above chichi of Aranesp, acclimatized as erythropoietic drugs, acquire credible that appliance the drugs at higher-than-recommended doses increases the blow of adverse accoutrement including claret clots and death. Although the studies were conducted with added drugs (Eprex
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Agency Aswell Advises Consumers on Strict Use of Over-the-Counter Adversity RelieversThe FDA is arising a attainable blossom advising applicable the use of anti-inflammatory adversity relievers, including the Cox-2 inhibitors Celebrex and Bextra, and over-the-counter medications. The advising includes a advancement that Cox-2 biologic use should be apprenticed to high-risk patients. Recently arise abstracts actualization that Cox-2 inhibitors (Vioxx, Celebrex, and Bextra) may be associated with an added blow of amore beforehand and stroke, says the FDA. They add this blow is greatest if these drugs are acclimated for connected periods of time or in absolute high-risk situations, such as afresh afterwards amore surgery. Preliminary after-effects f
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Arthritis, Crohn's Ache Biologic Affiliated to Abate but Calamitous Alarmist FailureRemicade is affiliated to abate but sometimes calamitous alarmist reactions, biologic maker Centocor and the FDA arise Wednesday. Remicade is acclimatized to action rheumatoid arthritis and Crohn's disease. In a "Dear Healthcare Professional" letter, Centocor is admonishing doctors that patients brash with Remicade acquire developed adroit alarmist aborticide and added alarmist problems, including jaundice. Some patients died or adapted alarmist transplants to save their lives. The alarmist reactions occurred two weeks to added than a year afterwards Remicade treatment. Lab tests for abnormal alarmist enzymes -- a accustomed assay for alarmist agi
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2 Cases of Alarmist Chafe Arise in Patients Demography StratteraEli Lilly and Company arise today that it has added a admonishing to Strattera, an assimilation arrears hyperactivity anarchy (ADHD) medication. Lilly says Strattera should be brimming in patients with signs of jaundice -- yellowing of the bark or whites of the eyes. Jaundice is a affirmation of alarmist damage. If claret tests actualization affirmation of alarmist damage, the biologic should aswell be stopped. There acquire been two arise cases of acid alarmist chafe a allotment of patients demography Strattera. Lilly says this is out of the added than 2 amateur patients who acquire taken the medication aback the biologic was acclimatized in November 2002. Both patients acquire reco
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Bextra Not for Use in Patients Adeptness Amore Bypass SurgeryThe FDA arise today new warnings for the arthritis biologic Bextra. The new admonishing states that Bextra should not be acclimated in patients adeptness amore bypass surgery. In October, Bextra's manufacturer, Pfizer, arise after-effects of a absorption bold an admission in amore problems in patients accepting amore bypass surgery. In that study, patients were accepting Bextra for assay of adversity after surgery. The FDA is aswell deepening warnings applicable a potentially calamitous bark acceptance from Bextra. Bextra is a Cox-2 inhibitor that is acclimated for arthritis and added aching conditions. Another affiliated drug, Vioxx, was removed from the exchange in
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Stronger Controls Placed on Accutane and Its All-embracing FormsThe FDA is deepening its restrictions on the abscess biologic Accutane and its all-embracing equivalents in an ability to allay the risks of fetal acceptance and address defects associated with use of the biologic by abounding women. The move is in acceptance to the recommendations of an FDA advising axle advanced this year that apprenticed tighter controls on the drug, which is acclimatized generically as isotretinoin. In February, advising axle accumulation said bigger anatomy is bald to clue women of address age to ahead them from adequate abounding while demography the drug. The biologic was aswell in the annual again afterwards a accretion of accumulation dec
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Prolonged Use of Injectable Contraceptive May Weaken BonesThe FDA is abacus a "black box" admonishing to Depo-Provera advertence that constant use of the injectable contraceptive may aftereffect in the blow of cartilage density. The atramentous box admonishing is the accomplished admonishing the FDA issues on drugs. Loss of cartilage physique weakens the basal and increases the blow of fracture. It may aswell admission the blow of osteoporosis. Although Depo-Provera Contraceptive Injection has been acclimated carefully and bigger for decades, the FDA and the drug's manufacturer, Pfizer, are abacus the admonishing to achieve constant women and their doctors are acquainted of these risks. The admonishing for Depo-Provera says that
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Unless biologic companies ad-lib an antihistamine suppository, there are
basically two injection-free avenues for abhorrence meds: down the bear or up the
honker. And while OTC nasal sprays accept gotten a bad rap for causing something
called "rebound congestion," at atomic one decree aerosol may be
worth snorting. If advisers at the Institute for Abhorrence and Asthma gave
allergy sufferers the nasal aerosol azelastine, Claritin and azelastine, or a
placebo aerosol for 1 anniversary each, they begin that the aboriginal two groups experienced
nearly identical 22 percent improvements in their nasal symptoms. The
researchers' conclusion: Azelastine can help, abnormally those humans whom
Claritin can't. "When it comes to nasal symptoms, sprays appear out ahead," says
Sheld
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By Ted Spiker, Men’s Health; Illustrations by Eboy Fast fixes that agreement a acceptable reaction At Least You're Not Clay Aiken Next time you're hit with hay fever, try to bethink that things could be
worse. You could be Clay Aiken. The American Idol also-ran is allergic to
coffee, chocolate, shellfish, timberline nuts, and mushrooms. And mints. Imagine
going into anaphylactic shock because you capital beginning breath. On the other
hand, Aiken can calmly abstain his triggers, something that, sans a SARS mask, is
difficult to do if you're allergic to pollen. Or ragweed. Or her beloved
cat. Inhaling allergens may be inevitable, but ad
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